PersonGen possesses a large-scale production platform for GMP-grade lentiviral vectors, which is based on cell lines developed through proprietary adaptation and optimization for the production of lentiviral vectors. These cells are characterized by their ability to adapt to high-density suspension culture, strong proliferative activity, and high virus production efficiency. To ensure high-quality and compliant viral vector products, PersonGen has established a series of advanced technical platforms:

· Process optimization and characterization platform for lentiviral vector production;

· Large-scale suspension cell culture and viral packaging platform;

· Large-scale viral purification platform;

· Aseptic filling platform for lentiviral vectors;

· Quality control and characterization platform for lentiviral vectors.

Additionally, PersonGen operates a large-scale GMP-grade plasmid production platform, providing critical raw materials for lentiviral vector manufacturing. To ensure high-quality and compliant plasmid products, PersonGen has also developed:

· Process optimization and characterization platform for plasmid production;

· Large-scale prokaryotic fermentation platform;

· Large-scale plasmid extraction and purification platform;

· Aseptic filling platform for plasmids;

· Quality control and characterization platform for plasmids.

PersonGen's plasmid and viral vector production platforms extensively utilize single-use technologies and automated equipment, significantly reducing the risk of cross-contamination while ensuring process consistency and stability.